It is used for the treatment of warts. The milky sap is squeezed on warts.

Caution: synadenium compactum has a burning effect. Caution should be taken when applying on warts. The use is similar to that of Sadenium grantlii
For asthma treatment, the leaves are dried, burned to ash, and licked, and a teaspoonful in the morning and in the evening. Alternatively, dried leaves are crushed, rolled into cigar,s and smoked. 

For treatment for goiter, the leaves are baked over a pan, then its juice is squeezed and mixed with honey then taken, 1 teaspoonful twice a day.